WebSep 2, 2024 · Cyclobenzaprine is a tricyclic amine salt that works in the central nervous system (CNS) as a depressant that reduces muscle … Webwith SSRIs and SNRIs. Discontinue Cymbalta and initiate supportive treatment (5.4, 7.14). • Abnormal Bleeding: Cymbalta may increase the risk of bleeding events. Patients should be cautioned about the risk of bleeding associated with the concomitant use of duloxetine and NSAIDs, aspirin, or other drugs that affect coagulation (5.5, 7.4). •
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